Sox10 is A Useful Marker for Triple Negative Breast Cancer
American journal of clinical pathology(2015)
Abstract
Triple negative breast cancers (TNBCs) are often aggressive neoplasms that are poorly differentiated, making confirmation that a metastasis is from a TNBC challenging. Many immunohistochemical (IHC) breast markers are specific but not sensitive, particularly in TNBCs. SOX10 is a nuclear transcription factor that is primarily used in diagnosing neuroectodermal tumors but that …
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