Anti-inflammatory and antinociceptive activity of Justicia gendarussa Burm. f. leaves
Indian Journal of Natural Products and Resources(2010)
摘要
The ethanolic extract of Justicia gendarussa Burm.f. leaves was screened for its anti-inflammatory and antinociceptive activity in experimental animals. The extract showed significant inhibition of carrageenan and formalin-induced paw oedema and cotton pellet-induced granuloma formation compared to the standard anti-inflammatory drug, Indomethacin. The extract at 125, 250 and 500 mg/kg showed significant inhibition of pain in the acetic acid-induced writhing and hot plate models in mice when compared to the standard analgesic drug, acetyl salicylic acid.
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关键词
antinociceptive activity,gendarussa burm,justicia,leaves,anti-inflammatory
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