The Impact Of Intramyocardial Mesenchymal Stem Cell Injection According To Scar Size For The Treatment Of Ischemic Cardiomyopathy

Makoto Natsumeda,Viky Y. Suncion,Wayne Balkan,Joshua M. Hare

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY（2016）

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摘要

Scar size is an important and easily assessed surrogate end point marker of cell therapy and has a larger fluctuation compared to conventional markers such as ejection fraction, enabling an accurate comparison.In three phase I/II randomized clinical trials, 57 patients [POSEIDON (n=30), TAC-HFT (n

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