Clinical Outcomes Of Rectal Carcinnids: A Single-Institution Experience

To report clinical outcomes of rectal carcinoids through investigating patients with rectal carcinoid. Between December 2011 and January 2003, 16 consecutive patients with biopsy-proven rectal carcinoid were enrolled at our institution, including ten males and six females, with a medial age of 49 years old (range 29 to 78 years). The median tumor size was 12.3mm, five lesions diameter were >= 20mm, eight lesions diameter were <= 10mm, three lesions diameter were 10mm-20mm. All rectal lesions were located within 10cm from the anal verge. 9 cases underwent transanal local excision; 3 cases had received anterior resection (Dixon); 2 cases underwent abdominaloperineal resection (APR); 2 cases underwent Endoscopic submucosal dissection (ESD). 2 of patients received postoperative chemotherapy or radiation therapy. Calculation of the 5-year overall survival (OS), recurrence-free survival (RFS) and cancer specific survival (CSS) were performed by Kaplan-Meier methodology. All patients were followed up for a median of 45.4 months (Range: 6 to 161 months), no patient was lost to follow-up. The 5-year OS, RFS and CSS were 85.2%, 93.8% and 90.9% respectively. Rectal carcinoids had a favorable prognosis, an adequate resection play key role in management of rectal carcinoid tumors, the extent of the surgical resection depend on its size, its anticipated stage and the specific patient needs. [Xiaoli Zheng, Yufei Lu, Siguo Cheng, Chengliang Yang, Hong Ge. Clinical Outcomes of Rectal Carcinoids: A Single-Institution Experience. Life Sci J 2012;9(4):1611-1614] (ISSN:1097-8135). http://www.lifesciencesite.com. 246