First Detection of the mcr-1 Colistin Resistance Gene in Escherichia coli in Italy

Antonio Cannatelli,Tommaso Giani,Alberto Antonelli,Luigi Principe,Francesco Luzzaro,Gian Maria Rossolini

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY（2016）

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摘要

Polymyxins are old antibiotics that have recently regained popularity for treatment of severe infections caused by extensively drug-resistant (XDR) Gram-negative bacterial strains ([1][1]). As a likely consequence, emergence of polymyxin resistance is being increasingly reported in the clinical

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