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CC5 and CC8, two homologous disintegrins from Cerastes cerastes venom, inhibit in vitro and ex vivo angiogenesis

Hazem Ben-Mabrouk,Raoudha Zouari-Kessentini, Fadoua Montassar, Zeineb Abdelkefi- Koubaa, Erij Messaadi,Xavier Guillonneau,Mohamed ElAyeb,Najet Srairi-Abid,José Luis,Olivier Micheau,Naziha Marrakchi

International Journal of Biological Macromolecules（2016）

Cited 15|Views18
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Abstract
Angiogenesis constitutes a fundamental step in tumor progression. Thus, targeting tumour angiogenesis has been identified to be promising in cancer treatment.
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Key words
Disintegrins,Angiogenesis,Anoïkis
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