Cholecystectomy Versus Expectant Management After Endoscopic Removal of Bile Duct Stone in Older People

tissues had significantly higher total scores compared to tissues from ECC patients without PSC, both in non-cancerous and cancerous tissues.In addition, PSC cases with biliary cancer tended to have a higher COX-2 score in non-cancerous bile duct epithelium compared to cases without biliary cancer.Conclusion: In PSC, overexpression of COX-2 was observed in non-cancerous and cancerous tissues; thus, COX-2 expression may be related to carcinogenesis in biliary cancer.