Differences Between Patient And Caregiver Ratings Of Advanced Cancer Patients' Quality Of Life And Correlates Of Their Disagreement.

9560 Background: Assessment of patient quality of life (QoL) by surrogates, particularly informal caregivers (e.g. spouse), is important to the care of advanced cancer patients. However, accuracy of such surrogate QoL assessments has been questioned. This study sought to assess differences between patients’ QoL self-assessments compared to assessments by their informal caregivers, and to determine characteristics associated with the disagreement. Methods: Data from 570 advanced cancer patient-caregiver dyads participating in the multi-site, Coping with Cancer study were included. Patients assessed their QoL with the McGill QoL questionnaire. Caregivers estimated patients’ QoL using the same questionnaire. Paired t-tests were used to compare the dyadic estimates of QoL scores. Multiple linear regression (MVA) was performed to examine factors potentially associated with the difference in dyadic QoL estimates. Results: Caregivers’ mean age was 53 years, 71% were female, and 51% were spouses. The overall mean...