The Broadly Neutralizing, Anti-HIV Antibody 4E10: an Open and Shut Case?

JOURNAL OF VIROLOGY（2016）

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摘要

Rujas et al. ([1][1]) recently studied the recognition mechanism of the anti-HIV antibody 4E10. We completely agree with their overall conclusion, that 4E10 “must recognize an antigenic structure more complex than just the linear α-helical epitope,” which echoes our own analysis ([2][2]): “

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