Lipid Profile And Clinical Outcomes In Acute Intracerebral Hemorrhage: The Samurai-Ich Study

Background and purpose: Although low serum total cholesterol (TC) levels are associated with an increased risk of intracerebral hemorrhage (ICH), the prognostic value of lipid parameters is not fully known. We aimed to determine the association between lipid parameters on admission and clinical outcomes in acute ICH patients. Methods: This study is a post-hoc analysis of the SAMURAI-ICH study, which was a prospective, multicenter, observational study. Hyperacute (hospitalized 33% increase), neurological deterioration (a decrease of ≥2 in GCS or an increase of ≥4 in NIHSS from baseline to 72 hours), favorable outcome (3-month mRS 0-2) and unfavorable outcome (3-month mRS 4-6). Results: Of the 204 patients (78 women; 66±12 years; median baseline NIHSS, 13 [8-17]), a stat...