An economic evaluation of a self-management programme of activity, coping and education for patients with chronic obstructive pulmonary disease

CHRONIC RESPIRATORY DISEASE(2016)

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摘要
The aim was to undertake a cost-utility analysis of a self-management programme of activity, coping and education (SPACE) for chronic obstructive pulmonary disease (COPD). The analysis was conducted alongside a six-month randomized controlled trial in 30 primary care settings. The economic analysis used data from 184 patients with confirmed diagnosis of COPD, forced expiratory volume in one second/forced vital capacity ratio <0.7 and with grade 2-5 on the Medical Research Council dyspnoea scale. Participants received either a self-management programme consisting of an education manual (SPACE for COPD) and consultation or usual care. Six-month costs were estimated from the National Health Service and Personal Social Services perspective and quality-adjusted life years (QALYs) were calculated based on patient responses at baseline and six months. The mean difference in costs between usual care and SPACE FOR COPD programme was -27.18 pound (95% confidence interval (CI); -122.59 pound to 68.25) pound while mean difference in QALYs was -0.10 (95% CI; -0.17 to -0.02). The results suggest that the intervention is more costly and more effective than usual care. The probability of the intervention being cost-effective was 97% at a threshold of 20,000 pound/QALY gained. We conclude that the SPACE FOR COPD programme is cost-effective compared to usual care.
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关键词
COPD,cost-effectiveness analysis,cost-utility analysis,RCT,self-management,education
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