Effects of treadmill exercise on mitochondrial fusion and fission in the hippocampus of APP/PS1 mice.
Neuroscience Letters（2019）
Abstract
•Treadmill exercise efficiently enhances learning and memory in APP/PS1 mice.•Treadmill exercise improves mitochondrial ultrastructure and functions in the hippocampus of APP/PS1 mice.•Treadmill exercise increased mitochondrial fusion and inhibited mitochondrial fission in the hippocampus of APP/PS1 mice.
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Key words
Alzheimer’s disease,Exercise,Learning and memory,Mitochondrial fusion and fission
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