Fibroblast-myofibroblast crosstalk after exposure to mesenchymal stem cells secretome.

Khadijeh Jalili Angourani,Sogol Mazhari,Shirin Farivar, Donya Salman Mahini,Abdolreza Rouintan,Kaveh Baghaei

Gastroenterology and hepatology from bed to bench（2018）

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摘要

Totally, Real Time PCR results suggest that MSCs conditioned medium activates differentiation of fibroblast to myofibroblast phenotype as confirmed through the presence of α-SMA, collagen I and collagen III expression compared to control in MRC 5 cells.

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关键词

Alpha-smooth muscle actin,Collagen I,Collagen III,Fibroblast,MSCs-secretome,Myofibroblast

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