Zinc inhibited LPS-induced inflammatory responses by upregulating A20 expression in microglia BV2 cells.

Li Hongxia,Tang Yuxiao,Shen Zhilei,Sun Yan,Qu Yicui, Shen Jiamin,Xu Xin,Yang Jianxin,Mo Fengfeng,Shen Hui

Journal of Affective Disorders（2019）

引用 27|浏览19

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摘要

•Zinc inhibited LPS-induce inflammation in BV2 microglia cells.•Zinc intervention protected viabilities of HT-22 hippocampus cells.•Zinc induced expression of anti-inflammatory regulator A20 in BV2 cells.

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关键词

Zinc,Neuroinflammation,A20,Microglia,NF-κB signaling pathway

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