[A Case of Solid Pseudopapillary Neoplasm of the Pancreas in a Male Patient].

The patient was a 50-year-old man. Abdominal ultrasound performed as part of a regular check-up suggested the presence of a tumor in the left kidney, and he was referred to our hospital for further examination. Computed tomography(CT) and magnetic resonance imaging(MRI)revealed the presence of a cystic neoplasm of the pancreas with partial calcification. The tumor had a maximum diameter of approximately 12 cm. Based on these findings, the patient was diagnosed with solid pseudopapillary neoplasm(SPN)and underwent distal pancreatectomy and splenectomy. Pathological findings indicated that a large proportion of the tumor was composed of cells with clear cytoplasm and small, oval nuclei, while some parts of the tumor were composed of atypical cells. Immunohistochemistry further demonstrated that the tumor expressed vimentin, nuclear b-catenin, and CD10. These findings confirmed the diagnosis of SPN. Atypical cells in the tumor were p53-positive, and some were exposed with damaged membranes. The patient has been followed up due to the possibility of tumor recurrence. The tumor has not recurred for approximately 32 months since surgery. Previous studies demonstrated that SPN is more common in women. We report the case of SPN in a male patient and discuss the literature.