Reconciling PC-MRI and CFD: An in-vitro study.

NMR IN BIOMEDICINE(2019)

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摘要
Several well-resolved 4D Flow MRI acquisitions of an idealized rigid flow phantom featuring an aneurysm, a curved channel as well as a bifurcation were performed under pulsatile regime. The resulting hemodynamics were processed to remove MRI artifacts. Subsequently, they were compared with CFD predictions computed on the same flow domain, using an in-house high-order low dissipative flow solver. Results show that reaching a good agreement is not straightforward but requires proper treatments of both techniques. Several sources of discrepancies are highlighted and their impact on the final correlation evaluated. While a very poor correlation (r(2) = 0.63) is found in the entire domain between raw MRI and CFD data, correlation as high as r(2) = 0.97 is found when artifacts are removed by post-processing the MR data and down sampling the CFD results to match the MRI spatial and temporal resolutions. This work demonstrates that, in a well-controlled environment, both PC-MRI and CFD might bring reliable and correlated flow quantities when a proper methodology to reduce the errors is followed.
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关键词
cardiovascular blood flows,computational fluid dynamics,large eddy simulation,phase contrast magnetic resonance imaging,validation work flow
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