Influence of ductal carcinoma in situ on the outcome of invasive breast cancer. A prospective cohort study.
International Journal of Surgery(2019)
Abstract
•IDC and IDC + DCIS are two different entities, coexisting ductal carcinoma in situ predicts lower tumor aggressiveness.•Only Grade I and II of invasive component was more frequent in patients with IDC + DCIS than that of IDC.•In patients receiving neoadjuvant chemotherapy, those with IDC + DCIS had lower response than those with IDC alone.•After neoadjuvant chemotherapy, longer disease free survival and overall survival was found when DCIS was present.
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Key words
Breast cancer,Ductal carcinoma in situ,Invasive ductal carcinoma,Prognosis factors
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