Anti-fibrotic effect of black tea (Camellia sinensis) extract in experimental pulmonary fibrosis.
Tissue and Cell(2019)
Abstract
•Black Tea Extract (BTE) reduces collagen deposition in pulmonary fibrosis.•BTE downregulates TGF-β expression in bleomycin-induced pulmonary fibrosis.•BTE inhibits the fibroblast to myofibroblast transformation in BIPF.•BTE upregulates IFN-γ expression in bleomycin-induced pulmonary fibrosis.•BTE affects on apoptotic markers in experimental pulmonary fibrosis.
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Key words
IPF,BIPF,BTE,TGF-β,TNF-α,IFN-γ,IL-,α-SMA,BALF,DAB,p.o.
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