Barley β-glucan accelerates wound healing by favoring migration versus proliferation of human dermal fibroblasts.

•Human fibroblasts treated with barley β-glucan undergo a short proliferation arrest.•Knocking-down RB1 in fibroblasts abolishes the β-glucan-induced proliferation arrest.•Barley β-glucan improves detachment and migration of human fibroblasts.•Topical addition of barley β-glucan enhances wound healing of the mouse skin.