Antioxidant imbalance and genotoxicity detected in fish induced by titanium dioxide nanoparticles (NpTiO 2 ) and inorganic lead (PbII).

Kézia Aguiar Delmond,Taynah Vicari,Izonete Cristina Guiloski, Ana Carolina Dagostim,Carmen Lúcia Voigt,Helena Cristina Silva de Assis,Wanessa Algarte Ramsdorf,Marta Margarete Cestari

Environmental Toxicology and Pharmacology（2019）

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摘要

•Assessment of the ROS imbalance and genotoxicity after co-exposure to Pb + NpTiO2.•Pb + NpTiO2 provoke ROS imbalances in liver tissue of Astyanax serratus.•Erythropoiesis in A. serratus was modified by necrosis induction.•Pb + NpTiO2 caused DNA damage in blood and liver of A. serratus.

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关键词

Biochemical biomarkers,Comet assay,Cytotoxicity,Metallic nanoparticles,Associated contamination

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