Diagnostic accuracy of loop-mediated isothermal amplification assay for extra-pulmonary tuberculosis in Indian population

Roopali Rajput,Paras Singh,Rohit Sarin,Prabhpreet Sethi,Sangeeta Sharma

Journal of Microbiological Methods（2019）

引用 7|浏览1

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摘要

•Molecular tests exhibit 4-fold higher TB positivity rate in EPTB specimens.•LAMP assay is more specific than nested PCR for EPTB diagnosis in children.•LAMP assay exhibited acceptable sensitivity in comparison to GenXpert.

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关键词

LAMP assay,Molecular diagnosis,Accuracy,EPTB,Children,PCR,Nested,Pediatric

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