Diagnostic accuracy of loop-mediated isothermal amplification assay for extra-pulmonary tuberculosis in Indian population
Journal of Microbiological Methods(2019)
Abstract
•Molecular tests exhibit 4-fold higher TB positivity rate in EPTB specimens.•LAMP assay is more specific than nested PCR for EPTB diagnosis in children.•LAMP assay exhibited acceptable sensitivity in comparison to GenXpert.
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Key words
LAMP assay,Molecular diagnosis,Accuracy,EPTB,Children,PCR,Nested,Pediatric
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