Chronic helminth infection does not impair immune response to malaria transmission blocking vaccine Pfs230D1-EPA/Alhydrogel® in mice.

•Pfs230 is a candidate malaria transmission blocking vaccine against P. falciparum.•Pfs230 vaccine is being tested in areas where malaria and helminth infections are co-endemic.•Chronic helminth infection induces a marked increase in systemic Th2 and regulatory cytokine levels in mice.•Chronic H. polygyrus bakeri infection does not alter Pfs230 vaccine specific-antibody levels.•Functional activity of Pfs230 vaccine was not impaired by chronic helminth infection in mice.