Hyperinsulinemia drives hepatic insulin resistance in male mice with liver-specific Ceacam1 deletion independently of lipolysis.

Metabolism（2019）

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摘要

•Mice with liver-specific Ceacam1 deletion manifest impaired insulin clearance followed by progressive insulin resistance

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关键词

Hyperinsulinemia,Insulin clearance,Insulin resistance,Hyperphagia,Fatty acid synthase,Energy balance

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