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Circulating biomarkers of left ventricular hypertrophy in pediatric coarctation of the aorta.

Benjamin S Frank,Tracy T Urban,Karlise Lewis,Suhong Tong,Courtney Cassidy,Max B Mitchell,Christopher S Nichols,Jesse A Davidson

CIRCULATION（2019）

Cited 7|Views16
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Abstract
Persistent left ventricular hypertrophy and abnormal relative wall thickness at intermediate-term follow-up was rare compared to previous studies. A model combining pre-op endothelin 1 and ST2 level demonstrated reasonable accuracy at predicting persistent abnormalities in this cohort. Larger studies will be needed to validate this finding and further explore the mechanism of persistent left ventricular remodeling in this population.
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Key words
Congenital heart disease,Biomarkers,Aortic coarctation,Endothelin,Hypertrophy
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