In vivo dynamic distribution of multivesicular bodies and exosomes in spleen of DTMUV infected duck.

Enxue Liu,Xuejing Sun,Xindong Wang,Taozhi Wang,Wenqian Li,Imran Tarique,Ping Yang,Qiusheng Chen

Veterinary Microbiology（2019）

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摘要

•The dynamic distribution of MVBs and exosomes in DTMUV-infected duck spleens were shown in vivo first.•Ultrastructural characterization of MVBs and exosomes were detected in duck spleen cells first.•DTMUV entry into the spleen cell by the clathrin-mediated endocytic pathways by utilizing MVBs and their exosomes.

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关键词

DTMUV,Spleen,MVBs,Exosomes,Endocytosis

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