Bilateral papillitis and vitritis as the initial ophthalmologic finding in a patient with complex medical history, leading to diagnosis of multisystem sarcoidosis.

This case highlights a 54-year-old woman with papillitis who presented with a complicated history and wide variety of systemic symptoms, creating a large differential diagnosis and challenging work up, ultimately resulting in a diagnosis of sarcoidosis via biopsy. The authors feel that papillitis is an underappreciated feature of ocular sarcoid.