Involvement of stromal cell-derived factor-1α (SDF-1α), stem cell factor (SCF), fractalkine (FKN) and VEGF in TSG protection against intimal hyperplasia in rat balloon injury.

Anling Hu,Juan Huang,Shiyue Li,Yang Gao,Li Wu,Jiang Deng, Jie Liu,Qihai Gong,Lisheng Li,Shangfu Xu

Biomedicine & Pharmacotherapy（2019）

Cited 13|Views11

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Abstract

•TSG inhibited intimal hyperplasia in rat common carotid artery balloon injury.•TSG reduced the expression of SCF/c-kit, SDF-1α/CXCR4 and FKN/CX3CR1 axes.•TSG enhanced re-endothelialization through increasing VEGF levels and CD34 cells.

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Key words

TSG,SCF,PCI,SDF-1α,FKN,VEGF,ELISA,PCNA,VSMCs,HUVECs,ECs,NIA,MA,IELA,H&E

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