Effects of AT-RvD1 on paraquat-induced acute renal injury in mice.
International Immunopharmacology(2019)
摘要
•It’s the first time to report that AT-RvD1 suppressed paraquat-induced oxidative stress by activating Nrf2 in renal tissue.•AT-RvD1 inhibited the interaction between neutrophils and platelets to reduce the infiltration of neutrophils.•AT-RvD1 inhibited the activation of NF-κB and the release of inflammatory cytokines in renal tissues.
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关键词
Paraquat,AT-RvD1,Acute renal injury
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