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Acid sphingomyelinase: No potential as a biomarker for multiple sclerosis.

C E Leurs,M A Lopes Pinheiro, L Wierts,S den Hoedt,M T Mulder,A J C Eijlers,M M Schoonheim,L J Balk,B M J Uitdehaag,J Killestein,H E de Vries

Multiple Sclerosis and Related Disorders（2019）

Cited 7|Views32
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Abstract
•Higher levels of acid sphingomyelinase activity in MS patients were found.•Acid sphingomyelinase activity did not correlate with activity, progression or therapy response.•Two ceramides and four types of sphingomyelin require further investigation as potential markers.
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Key words
Multiple sclerosis,Biomarkers,Sphingomyelins,Sphingolipids,Fingolimod
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