Annexin A2 associates to feline calicivirus RNA in the replication complexes from infected cells and participates in an efficient viral replication.
Virus Research(2019)
Abstract
•AnexA2 is in vitro associated with the 3′UTR from the FCV RNA.•AnxA2 is associated with the viral RNA in the replication complexes from FCV.•AnxA2-knockdown causes a reduction in FCV protein and dsRNA production.•AnxA2-knockdown causes a decrease of FCV production.•AnxA2 is required for an efficient FCV production.
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Key words
Feline calicivirus,Annexin A2,RNA-protein interaction,Viral replication,Replication complexes
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