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Unravelling the brain networks driving spike-wave discharges in genetic generalized epilepsy-common patterns and individual differences.

Silke Klamer,Thomas Ethofer, Franziska Torner,Ashish Kaul Sahib,Adham Elshahabi,Justus Marquetand,Pascal Martin,Holger Lerche,Michael Erb,Niels K Focke

Epilepsia open（2018）

Cited 10|Views3
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Abstract
The observed interplay between DMN, DAN, SN, and thalamus may indicate a downregulation of consciousness. The DMN seems to play a leading role as a driving force behind these changes. Overall, however, there were also clear differences in activation patterns between patients, reflecting a certain heterogeneity in this cohort of GGE patients.
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Key words
Default mode network,Dynamic causal modelling,Generalized spike‐wave discharges,Genetic generalized epilepsy,Thalamus
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