Simultaneous and specific enrichment of several amphenicol antibiotics residues in food based on novel aptamer functionalized magnetic adsorbents using HPLC-DAD.

•A novel aptamer functionalized magnetic adsorbent was developed for selective enrichment of three amphenicols in complex food matrix.•Dispersive solid phase extraction method coupling with the adsorbent was employed for detection 0.1ng/ml of amphenicols in milk.•This assay is environmentally friendly and time-saving due to without using organic reagent and purifying.