Utility of serum DNA as a marker for KRAS mutations in pancreatic cancer tissue.

Soichiro Ako,Kazuhiro Nouso,Hideaki Kinugasa,Chihiro Dohi,Hiroshi Matushita,Sho Mizukawa,Shinichiro Muro,Yutaka Akimoto,Daisuke Uchida,Takeshi Tomoda,Kazuyuki Matsumoto,Shigeru Horiguchi,Koichiro Tsutsumi,Hironari Kato,Hiroyuki Okada

Pancreatology（2017）

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摘要

Serum and plasma were found to be good materials for detecting cancer-specific DNA in the peripheral blood and the presence of KRAS mutations in blood-derived DNA may be used as a prognostic biomarker for patients with pancreatic cancer.

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关键词

KRAS,Droplet digital polymerase chain reaction,Liquid biopsy,Pancreatic cancer

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