Bath-PUVA therapy improves impaired resting regulatory T cells and increases circulating activated regulatory T cells in psoriasis
Journal of Dermatological Science(2016)
摘要
•Psoriasis may be due to a regulatory T cell (Treg) imbalance.•Bath-psoralen plus ultraviolet light A (PUVA) therapy is effective for psoriasis.•Activated Treg, which suppress psoriatic activity, are increased by Bath-PUVA.•Resting Treg, which are low in psoriasis patients, are increased by Bath-PUVA.•Bath-PUVA may improve the Treg imbalance in psoriasis.
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关键词
aTreg,Foxp3,IL,non-Treg,PASI,PUVA,rTreg,Th17,Treg,RORγ t,DAS-28,IFX
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