Involvement of water channel Aquaporin 5 in H 2 S-induced pulmonary edema.
Environmental Toxicology and Pharmacology（2017）
Abstract
•H2S significantly contributed to lung injury.•H2S obviously increased AQP5 expression in A549 cell line and mouse lung tissues.•MAPK signaling pathways were involved in H2S-induced AQP5 expression
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Key words
Hydrogen sulfide,Aquaporin 5,ERK1/2,JNK,p38 MAPK,Pulmonary edema
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