Endogenous erythropoietin and erythropoietin receptors in colorectal cancer; can we answer the questions?

Aleksandar Čubranić,Renata Dobrila-Dintinjana,Arnela Redžović,Marijan Dintinjana,Duška Petranović,Marin Golčić

Medical Hypotheses（2016）

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摘要

Erythropoietin (Epo) is glycoprotein hormone which binds on erythropoietin receptors (EpoR) promoting proliferation and differentiation. Studies have shown that EpoR, apart from erythrocyte precursors, is expressed on no hematopoietic tissue and various tumor cells.

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关键词

CEA,CRC,EMT,Epo,EpoR,,HCC,HIF-1α,MV,TNM,VEGF

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