Differential expression of Low density lipoprotein Receptor-related Protein 1 (LRP-1) and matrix metalloproteinase-9 (MMP-9) in prostate gland: From normal to malignant lesions.

Mónica B Gilardoni,María M Remedi,Mabel Oviedo,Tristán Dellavedova,Juan P Sarría, Laura Racca, Mariana Dominguez,Claudia G Pellizas,Ana C Donadio

Pathology - Research and Practice（2017）

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摘要

Considering that LRP-1, by mediating the clearance of MMPs, is involved in the regulation of ECM remodeling and cell migration, we conclude that a decreased expression of LRP-1 could be involved with the increasing activity of MMPs shown in cancers.

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关键词

Prostate,Cancer,LRP-1,MMP-9,Immunohistochemistry,Zymography

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