The injury of fine particulate matter from cooking oil fumes on umbilical cord blood vessels in vitro.

Environmental Toxicology and Pharmacology(2017)

Cited 19|Views10
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Abstract
•COFs-derived PM2.5 increased oxidative stress, inflammation and dysfunction of UCs.•HIF-1α/iNOS/NO and VEGF/VEGFR1/iNOS signaling pathways were involved in UCs injury.•UC damage induced by PM2.5 plays a vital role in maternal-fetal material transport.
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Key words
Cooking oil fumes,PM2.5,Umbilical cord blood vessels,HIF-1α and VEGF
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