Pancreatic duct stenosis: Differential diagnosis between malignant and benign conditions at secretin-enhanced MRCP.

•A mass forming lesion with main pancreatic duct stenosis could be a challenge for the radiologist.•Secretin administration during MRCP increases the accuracy of MRI to distinguish between benign and malignant conditions.•A single complete stenosis with dilated side branches is highly suggestive of malignancy.•Absent duct penetrating at S-MRCP is the most suggestive sign of malignancy.