[CD8 and FOXP3 expression in stromal tumor-infiltrating lymphocytes of triple-negative breast carcinomas: a clinicopathologic study].
Zhonghua bing li xue za zhi = Chinese journal of pathology（2016）
Abstract
The percentage of stromal TILs and density of CD8(+) CTL are associated with tumor cell proliferation of triple-negative breast cancers. The density of FOXP3(+) Treg is significantly associated with poor prognosis. Stromal TIL is positively correlated with the density of CD8(+) CTL. Stromal TIL may provide a potential marker for pathological diagnosis and a target for guiding adjuvant therapy in patients with triple-negative breast cancers.
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Key words
Breast neoplasms,Lymphocytes,tumor-infiltrating,T-lymphocyte,cytotoxic,CD8-positive T-lymphocytes,T-lymphocytes,regulatory
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