Lacrain: the first antimicrobial peptide from the body extract of the Brazilian centipede Scolopendra viridicornis

International Journal of Antimicrobial Agents(2016)

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摘要
•A new antimicrobial from the whole body extract of the Brazilian Chilopoda Scolopendra viridicornis is described.•Lacrain presents specific activity against Gram-negative bacteria.•Lacrain is a peptide with a sequence of 8 amino acid residues (RYPAVGYT) and a molecular mass of 925.5 Da.•This peptide does not show cytotoxic activity against human erythrocytes.•This new molecule is the first described peptide with antimicrobial activity from the body extract of a myriapod.
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关键词
Scolopendra viridicornis,Myriapoda,Centipede,Body extract,Antimicrobial peptide,Immune system
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