A spermine conjugated stearic acid-g-chitosan oligosaccharide polymer with different types of amino groups for efficient p53 gene therapy.

Tingting Meng,Jie Wu,Hanxi Yi,Jingwen Liu,Binbin Lu,Ming Yuan,Xuan Huang,Hong Yuan,Fuqiang Hu

Colloids and Surfaces B: Biointerfaces（2016）

引用 19|浏览5

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摘要

Formation and function process of the gene complexes based on stearic acid (SA) and spermine (SP) modified chitosan oligosaccharide (SP-CSOSA) polymer.

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关键词

Spermine,Gene delivery system,Endo-lysosomal escape,Transfection efficiency,p53 Gene therapy

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