[The activation of microglia caused by lead and manganese co-exposure induces activation of astrocytes and decrease of glutamine synthetase activity].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology(2016)
Abstract
Low-level lead or manganese alone or their co-exposure can cause microglia activation. The activated microglia can induce astrocyte activation and reduce its GS expression. Furthermore, compared with exposure alone, co-exposure had a synergistic effect.
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Key words
microglia,astrocytes,glutamine synthetase activity,manganese,co-exposure
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