Correlations Of O-3 Therapeutic Targets And Imaging Localization In Lumbar Intervertebral Disc Protrusion

Objective: This study aims to investigate correlations between the effects of O-3 target-injection treatment and imaging localization in lumbar intervertebral disc protrusion (LIDP). Methods: 164 LIDP patients were divided into 3 groups: group A, the protrusion located at level I-III, region 1-2, domain a-b; group B, the protrusion located at level I-III, region 1-2, domain c-d; group C: the protrusion located at level I-III, region 3-4, domain a-b. The patients were treated with LIDP O-3-target treatment + blocking therapy with epidural anti-inflammatory analgesic liquid. Results: Among the 164 LIDP patients, 95 patients (57.93%) exhibited the significant effectiveness after the treatment; 64 cases (39.02%) exhibited the effectiveness. The results of functional improvements revealed that 50 cases (53.76%) of sagittal plane and 54 cases of horizontal plane (55.67%) in the group A, 33 cases (35.48%) and 31 cases (31.96%) in the group C respectively were significantly better than those in the group B (10 cases, 10.75%; 12 cases, 12.37%) (P < 0.05). The visual analogue scale (VAS) scores 1 week and 1 month after the treatment in the three groups were significantly decreased than those before the treatment (P < 0.05). The intergroup comparison revealed that the A group (1 week 2.28 +/- 0.85, 1 month 1.21 +/- 0.27) and C (2.79 +/- 0.98, 1.38 +/- 0.55) were significantly better than the B group (3.92 +/- 1.14, 2.53 +/- 0.51) (P < 0.05). Conclusions: The O-3 target-injection treatment exhibited the best effects in treating the LIDP patients with the protrusion located at level I-III, region 1-2, domain a-b.