Antibody-based donor-acceptor spatial reconfiguration in decorated lanthanide-doped nanoparticle colloids for the quantification of okadaic acid biotoxin.

Filip Stipić,Petra Burić,Željko Jakšić,Galja Pletikapić,Maja Dutour Sikirić,Goran Zgrablić,Leo Frkanec,Daniel M Lyons

Colloids and Surfaces B: Biointerfaces（2015）

引用 10|浏览22

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摘要

•Colloidal chemistry with LRET allowed the detection of biotoxins.•Ligands were used to tailor the surface binding and orientation of antibodies.•Binding of okadaic acid resulted in concentration-dependent LRET.

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关键词

Biosensor,Diagnostic,Nanoparticle,Lanthanide,Immunoassay,Point-of-care

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