ETANERCEPT AS TREATMENT OF STEROID-REFRACTORY ACUTE GRAFT VERSUS HOST DISEASE IN PEDIATRIC PATIENTS.

Maura Faraci,Maria Grazia Calevo,Stefano Giardino,Massimiliano Leoni,Erica Ricci, Elio Castagnola,Edoardo Lanino

Biology of Blood and Marrow Transplantation（2019）

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摘要

•The overall response rate to etanercept (ET) in children with steroid-refractory acute graft-versus-host disease (SR aGVHD) was 68%.•The better response was obtained in cutaneous and gastrointestinal SR aGVHD.•Overall survival in responders was 76.5% (P = .004).•ET represents an effective treatment of SR aGVHD with a high response rate.

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关键词

Etanercept,Refractory acute graft-versus-host disease,Children

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