The DNA damage response is developmentally regulated in the African trypanosome.

J P Vieira-da-Rocha,D G Passos-Silva,I C Mendes,E A Rocha,D A Gomes,C R Machado,R McCulloch

DNA Repair（2019）

引用 9|浏览23

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摘要

•DNA repair kinetics evaluated in T. brucei nuclear and mitochondrial genomes.•Higher efficiency of DNA repair in T. brucei cells from the mammal than the tsetse.•Differing cell cycle and survival responses to DNA damage in two T. brucei cell types.•Mitochondrial DNA repair is active in T. brucei and can involve RAD51.

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关键词

BER,BSF,DR,DSBs,HR,ICL,kDNA,MMR,MMS,nDNA,NER,NHEJ,PCF,PI,TLS,VSG

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