Short- and long-term alterations of FKBP5-GR and specific microRNAs in the prefrontal cortex and hippocampus of male rats induced by adolescent stress contribute to depression susceptibility.

•Adolescent stress induced constant depressive-like behaviors and memory impairment.•Adolescent stress reduced GR levels persistently.•Adolescent stress elevated FKBP5 levels persistently.•Adolescent stress increased miR-124a and miR-18a expressions persistently.•Adolescent stress decreased miR-511 levels only in the prefrontal cortex of adult rats.