Toll-like receptor 9 polymorphisms and Hepatitis B virus clearance in Moroccan chronic carriers.

Gene(2019)

引用 12|浏览8
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摘要
•TLR9 promoter polymorphisms are not associated with spontaneous HBV clearance.•The TLR9 polymorphisms may influence the circulating HBV DNA.•TLR9 rs187084 AA HBV carriers are more likely to progress to advanced liver disease.
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关键词
IgM,IL-6,PRRs,RLRs,NOD-like receptors,CpG,MYD88,IRAK,NF-κB,AP-1,TRAF6,PBMCs,IRF7,SOCS-1,BDCA2
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