Effect of PF-04634817, an Oral CCR2/5 Chemokine Receptor Antagonist, on Albuminuria in Adults with Overt Diabetic Nephropathy.

Jeremy D Gale,Steven Gilbert,Samuel Blumenthal,Tom Elliott,Pablo E Pergola,Kosalaram Goteti,Wim Scheele,Christelle Perros-Huguet

Kidney International Reports（2018）

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摘要

Despite the good safety profile shown by PF-04634817, clinical development for this indication was discontinued in light of the modest efficacy observed.

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关键词

albuminuria,CCR2,CCR5,diabetes,diabetic nephropathy

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